About Us

Forget what you thought you knew about NGS targeting workflows.

Molecular Loop brings elegant simplicity to targeted NGS.

Our Mission

We deliver targeted NGS technology that works and is easy to use. Our simple solutions will accelerate innovation and make genetic testing even more accessible. Easy on your staff. Simplifying the lab.

Molecular Loop’s patented technology was developed over many years to enable high-accuracy, ultra high-throughput NGS sequencing solutions for clinical applications and large-scale research projects. We specialize in developing production-grade chemistry that simplifies the workflow, reduces cost and time, significantly increases throughput, and delivers high-quality results. The technology has been used extensively in clinical studies and has a strong publication record.

Our Team

NGS veterans with battle-hardened and field-tested technology

Greg Porreca Molecular Loop

Greg Porreca, Ph.D.

Co-founder, President & CEO

Greg was previously co-founder and CTO of Good Start Genetics, a genetic testing laboratory acquired by Invitae Corporation (NYSE: NVTA). Greg earned his PhD in Genetics in the lab of George Church at Harvard where he invented and built one of the first next-generation DNA sequencing platforms. He holds a bachelor's degree in Biology and Computer Science from The College of New Jersey, is a co-author of numerous high-impact publications on genomics technology, and a co-inventor on over 40 issued and pending patents.

In his free time, Greg loves hiking and skiing with his family in the White Mountains of New Hampshire.

Eric Boyden Molecular Loop

Eric Boyden, Ph.D.

Co-founder and Head of Research, Development, and Innovation

Eric previously was Principal Scientist at Invitae Corporation and Good Start Genetics, where he led the development of automated high-throughput genetic assays and analysis algorithms for clinical NGS applications. Eric earned a BS in Molecular Biology at the University of Connecticut and a Ph.D. in Genetics at Harvard University, trained in next-generation sequencing and bioinformatics during a postdoctoral fellowship at Boston Children's Hospital, has co-authored several gene discovery papers in prominent journals, and is an inventor on several pending or issued patents.

When not working he likes to go camping in western Massachusetts or swimming on Cape Cod with his family.

Bob King Molecular Loop

Bob King

Director of Sales

Bob has many years of experience in the Women’s Health and genetic testing space. He previously worked for EMD Serono, was part of the initial commercial team at Natera and Good Start Genetics as Director of New Business and Strategic Accounts. He has a BS in Marketing from East Carolina University and has led many successful product launches.

In his spare time, Bob enjoys spending time with his wife and two daughters and boating and fishing in Cape May County, New Jersey.

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Pat Saunders Molecular Loop

Pat Saunders

Head of Product Implementation

Pat was previously Technical Project Manager at Ovia Health and HighRes Biosolutions and Manager of Laboratory Automation at Good Start Genetics. He has overseen the development and delivery of numerous automated HTP platforms for academic and commercial use around the world. He holds a BS in Neurobiology and Neurosciences from Northeastern University and graduate credit in Computer Science and Business Management from the Harvard Extension School.

Pat spends his free time with his family on Cape Cod and mountain biking in the Green Mountains of Vermont.

Molecular Loop Technology Timeline

2007
2012
2014
2016
2017
2018
Initial publication of MIP technology for targeted NGS
Initial clinical user lauch of Good Start Genetics' first carrier screening offering
Publication of analytical validation of MIP technology for carrier screening
Good Start Genetics offers MIP-based carrier screening
Invitae acquires Good Start Genetics, including MIP technology
Molecular Loop acquires MIP technology from Invitae

Publications

Porreca, G. J., K. Zhang, J. B. Li, B. Xie, D. Austin, S. L. Vassallo, E. M. LeProust et al. “Multiplex amplification of large sets of human exons.” Nature methods 4, no. 11 (2007): 931-936.

Umbarger, M. A., C. J. Kennedy, P. Saunders, B. Breton, N. Chennagiri, J. Emhoff, V. Greger et al. “Next-generation carrier screening.” Genetics in Medicine 16, no. 2 (2014): 132-140.

Hallam, Stephanie, et al. “Validation for clinical use of, and initial clinical experience with, a novel approach to population-based carrier screening using high-throughput, next-generation DNA sequencing.” The Journal of Molecular Diagnostics 16, no. 2 (2014): 180-189.