About Us

Forget what you thought you knew about NGS targeting workflows.

Molecular Loop brings elegant simplicity to targeted NGS.

Our Mission

We deliver targeted NGS technology that works and is easy to use. Our simple solutions will accelerate innovation and make genetic testing even more accessible. Easy on your staff. Simplifying the lab.

Molecular Loop’s patented technology was developed over many years to enable high-accuracy, ultra high-throughput NGS sequencing solutions for clinical applications and large-scale research projects. We specialize in developing production-grade chemistry that simplifies the workflow, reduces cost and time, significantly increases throughput, and delivers high-quality results. The technology has been used extensively in clinical studies and has a strong publication record.

Our Team

NGS veterans with battle-hardened and field-tested technology

Greg Porreca, Ph.D.

Co-founder, President & CEO

Greg was previously co-founder and CTO of Good Start Genetics, a genetic testing laboratory acquired by Invitae Corporation (NYSE: NVTA). Greg earned his PhD in Genetics in the lab of George Church at Harvard where he invented and built one of the first next-generation DNA sequencing platforms. He holds a bachelor's degree in Biology and Computer Science from The College of New Jersey, is a co-author of numerous high-impact publications on genomics technology, and a co-inventor on over 40 issued and pending patents.

In his free time, Greg loves hiking and skiing with his family in the White Mountains of New Hampshire.

Eric Boyden, Ph.D.

Co-founder and Head of Research, Development, and Innovation

Eric previously was Principal Scientist at Invitae Corporation and Good Start Genetics, where he led the development of automated high-throughput genetic assays and analysis algorithms for clinical NGS applications. Eric earned a BS in Molecular Biology at the University of Connecticut and a Ph.D. in Genetics at Harvard University, trained in next-generation sequencing and bioinformatics during a postdoctoral fellowship at Boston Children's Hospital, has co-authored several gene discovery papers in prominent journals, and is an inventor on several pending or issued patents.

When not working he likes to go camping in western Massachusetts or swimming on Cape Cod with his family.

Pat Saunders

Head of Product Implementation

Pat was previously Technical Project Manager at Ovia Health and HighRes Biosolutions and Manager of Laboratory Automation at Good Start Genetics. He has overseen the development and delivery of numerous automated HTP platforms for academic and commercial use around the world. He holds a BS in Neurobiology and Neurosciences from Northeastern University and graduate credit in Computer Science and Business Management from the Harvard Extension School.

Pat spends his free time with his family on Cape Cod and mountain biking in the Green Mountains of Vermont.

Lindsay Wold

Head of Sales

Lindsay has nearly 15 years of experience in the Life Science industry and has been supporting sequencing applications for the last 7 years. She was a part of the commercial team that launched the Ion Torrent platform and then moved on to work with Kapa Biosystems to help bring their library prep kits mainstream. She recently joined Molecular Loop from Roche Diagnostics, where she led a team supporting the Roche Sequencing portfolio. Lindsay earned her BSc in Genetics from the University of Alberta and her MSc in Molecular Biology from Staffordshire University.

Outside of work, Lindsay loves staying active with her family, whether it be living room workouts or hikes in the Redwoods. She also loves a good book and a good game of hockey.

Contact Me

Molecular Loop Technology Timeline

2007

2012

2014

2016

2017

2018

Initial publication of MIP technology for targeted NGS

Initial clinical user lauch of Good Start Genetics' first carrier screening offering

Publication of analytical validation of MIP technology for carrier screening

Good Start Genetics offers MIP-based carrier screening

Invitae acquires Good Start Genetics, including MIP technology

Molecular Loop acquires MIP technology from Invitae

Publications

Porreca, G. J., K. Zhang, J. B. Li, B. Xie, D. Austin, S. L. Vassallo, E. M. LeProust et al. “Multiplex amplification of large sets of human exons.” Nature methods 4, no. 11 (2007): 931-936.

Umbarger, M. A., C. J. Kennedy, P. Saunders, B. Breton, N. Chennagiri, J. Emhoff, V. Greger et al. “Next-generation carrier screening.” Genetics in Medicine 16, no. 2 (2014): 132-140.

Hallam, Stephanie, et al. “Validation for clinical use of, and initial clinical experience with, a novel approach to population-based carrier screening using high-throughput, next-generation DNA sequencing.” The Journal of Molecular Diagnostics 16, no. 2 (2014): 180-189.