Infectious Disease Surveillance
Relied on by leading labs during the COVID pandemic
Robust, scalable viral surveillance tools
There is a reason why leading labs chose Molecular Loop during the SARS-CoV-2 pandemic — our targeted library prep technology is uniquely equipped to capture rapidly mutating viruses.
Redundant probe tiling, a key element of the Molecular Loop approach, allows for the detection of emerging variants by minimizing problematic amplicon dropouts that are common with conventional PCR technologies. This robustness is paired with a simple 4-step workflow making our solution easy to implement and scale for Illumina, PacBio, and other sequencing platforms.
Simple Workflow for RNA and DNA Inputs
4-step workflow with only 75 minutes of hands-on time
Reverse transcription of viral RNA is built into the first step with probe annealing. No bead washes and 4 simple steps makes the workflow easy to perform manually or with automation.
Overlapping amplicons provide redundant coverage to minimize amplicon dropouts
Every targeted region is covered by multiple probes with non-overlapping priming sites. This tiling approach mitigates the impacts of new variants that can otherwise lead to uneven coverage or amplicon dropouts in PCR-based methods.
Molecular Loop offers off-the-shelf panels that can get you off to a quick start
All panels provide comprehensive coverage of the viral genome and are available for Illumina, PacBio, and other platforms. Contact us if you don’t find what you are looking for!
